Research on Psychedelic Microdosing Risks is Limited

  • SOURCE ▸
    PUBLISHED
  • January 1, 2020
  • AUTHORS
  • Toby Lea, Nicole Amada, Henrik Jungaberle
  • PUBLICATION
  • International Journal of Drug Policy
  • TITLE
  • Research on Psychedelic Microdosing Risks is Limited
  • Microdosing psychedelics: Motivations, subjective effects and harm reduction
  • KEY TAKEAWAY
  • Regular microdosing of psychedelics may offer perceived short-term benefits for mental health and cognitive performance, but it's crucial to understand the motivations, dosing practices, potential unwanted effects, and harm reduction strategies due to limited research evidence.

Introduction

Microdosing psychedelics has become a popular practice for enhancing cognitive performance, improving mental health, and aiding personal development. Despite its illegal status in many jurisdictions, individuals are turning to microdosing as a self-managed therapy for mental health conditions.

Motivations and Practices

A study on microdosing revealed that individuals primarily microdose to improve mental health, for personal development, and cognitive enhancement. Psilocybin and LSD are the most common substances used for microdosing. Participants reported short-term benefits such as improved mood, anxiety, enhanced connection, and cognitive enhancement. However, potential negative effects were also noted, including unexpected psychedelic effects, anxiety-related effects, and physical adverse effects.

Implications and Challenges

Many individuals are using microdosing as a self-managed therapy for mental health issues, often due to a lack of adequate conventional treatments. Clinical trials suggest the potential of standard psychedelic doses for treating depression and anxiety, indicating that microdosing may have neurobiological effects beyond a placebo. However, the legal status of psychedelics presents a barrier to widespread adoption and highlights the need for further research, including randomized controlled trials and harm reduction resources.

Harm Reduction and Safety

Insights into the motivations and experiences of individuals who microdose emphasize the importance of informed harm reduction practices. Nonprofit organizations dedicated to psychedelic harm reduction can help guide the public in the responsible use of these substances by emphasizing safety, legal considerations, and evidence-based practices in discussions about microdosing for mental health self-care and cognitive enhancement strategies.

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