The study titled "Psychedelics and workplace harm" by S. M. Viña and A. L. Stephens, published in 2023 in Frontiers in Psychiatry, explores the intricate relationship between Lifetime Classic Psychedelic Use (LCPU), employment status, and weekly work hours, examining their impact on levels of psychological distress. Utilizing data from the National Survey of Drug Use and Health (NSDUH) spanning from 2008 to 2019, which included a considerable sample size of 484,732 individuals, the study delves into how these factors correlate with psychological well-being.Key findings from this comprehensive analysis reveal that both LCPU and being employed are independently linked to improved psychological health outcomes. Specifically, the study highlights that individuals who have used psychedelics and are employed, volunteering, retired, or permanently disabled tend to experience lower levels of psychological distress. This suggests a potential protective effect of psychedelic use in certain demographic segments. Conversely, for those who are unemployed, full-time students, or homemakers, psychedelic use may be associated with heightened levels of distress, indicating a complex interaction between psychedelic use and various life circumstances.Interestingly, the research also uncovers that individuals who engage in psychedelic use tend to work longer hours before encountering an increase in stress levels. This finding points to a nuanced understanding of the relationship between work, psychedelic use, and psychological distress, suggesting that psychedelic use might contribute to a higher tolerance for work-related stress under certain conditions.Overall, the study provides compelling evidence that the use of psychedelics does not uniformly lead to negative employment outcomes. Instead, it indicates a potentially beneficial role of psychedelics in enhancing psychological resilience among employed and engaged individuals, while also underscoring the importance of considering individual employment status and life circumstances when assessing the impact of psychedelic use on psychological well-being. This research contributes significantly to the ongoing discourse on psychedelic harm reduction, safety, and their relevance in the context of employment and psychological health, underscoring the nuanced and varied impacts of these substances across different facets of life (S. M. Viña & A. L. Stephens, 2023).