The Psychedelic Safety Institute (PSI) was contracted by Gather Well Psychedelics to create and operationalize an ethics framework to hold Gather Well accountable to their stated ethical principles and address risk of future ethical violations. This framework, informed by bioethicists and stakeholders, includes robust informed consent procedures, codes of conduct, grievance protocols, and independent oversight structures. While PSI’s work with Gather Well does not constitute an endorsement, the project provided a valuable case study to advance ethical standards across the field. PSI remains committed to improving ethical practices within the psychedelic ecosystem through collaboration, transparency, and real-world application.